They can go up and down for no obvious reason. They can rise after treatment. And levels tend to be higher in older men and those with large prostates. What makes PSA go down? There are several factors that may cause a lowered PSA level as well. Patients who are overweight, frequently take aspirin, or use certain cholesterol-lowering drugs may Participants with elevated PSA levels or abnormal rectal exams were sent for a prostate biopsy. The study found that PSA levels dropped significantly in people taking finasteride for more than one year compared to the placebo group. PSA values dropped by 5% in people without prostate cancer, but up to 15% in those with prostate cancer. Objective: To investigate the effect of SARS CoV-2 on serum total PSA levels in men with BPH diagnosed with COVID-19. Methods: The PSA (Kit: Immunoassay Program- Cycle 18, Siemens Atellica IM Analyzer) levels in patients who had had a PSA check at least 3 months, but no more than 6 months, prior to diagnosis of acute COVID-19 infection, were examined retrospectively. Posts : 2. Posted 2/21/2013 11:04 AM (GMT -8) Hello. I had a recent blood test as part of my annual physical and the results showed my PSA jumped 2.2 to 3.9. I will be 43 years old in March. I went back to my doctor to discuss the results and he did another DRE and didn't find any nodules or masses. His PSA was 7.4, Gleason score 10. The cancer had spread to his spine, a rib and seminal pouches. After a few hormone injections his PSA dropped to 1.1. In October he started having problems passing urine again and his PSA had started to rise again. The oncologist arranged a course of radiotherapy to start 1st of December 14 but bat the end of Prostate-Specific Antigen. Ejaculation causes a significant increase in the serum PSA concentration in men between 49 and 79 years of age that may persist for up to 48 hours. This change appears to correlate with age and baseline PSA. It is recommended that men abstain from ejaculation for 48 hours prior to having a serum PSA …. PSA levels depend on age. If you have a prostate, your PSA levels naturally go up as you get older. But PSA can go up and down for many reasons. Most labs consider a normal PSA level to be around 4 ng/mL. Some researchers use a lower cut-off PSA level to help them decide who has the greatest risk of prostate cancer. The prostate specific antigen (PSA) blood test measures the amount of prostate specific antigen in your blood. PSA is a protein that is made by the cells in your prostate gland. The prostate is part of the male reproductive system. Most of the PSA made is released into semen but some goes into your blood. High levels of PSA can be caused by As elevated serum PSA level is one of the most proven predictors of AUR episodes in patients with BPH, checking the serum PSA during and after pandemic in patients with old age affected by COVID Bounce PSA is not well understood yet and many link the fact to infection or inflammation at prostatic tissues. Your cases could be just that of a low level infection which could be treated with a dose of antibiotics, bringing down the PSA. Best wishes for a lower PSA in your next test and peace of mind. VGama NRtynL.